Preclinical safety assessment of glycosides based standardized fenugreek seeds extract: Acute, subchronic toxicity and mutagenicity studies
نویسندگان
چکیده
منابع مشابه
Preclinical safety assessment of glycosides based standardized fenugreek seeds extract: Acute, subchronic toxicity and mutagenicity studies
Article history: Received on: 29/03/2016 Revised on: 07/07/2016 Accepted on: 08/08/2016 Available online: 26/09/2016 Objective: To evaluate acute oral toxicity (AOT), subchronic toxicity, and mutagenic potential of glycosides based standardized fenugreek (Trigonella foenum graecum L.) seeds extract (SFSE-G). Materials and Methods: The AOT, subchronic (90-day repeated dose) toxicity and mutageni...
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CONTEXT Glycoside-based standardized fenugreek seed extract (SFSE-G) demonstrated promising efficacy in animal models of immune-inflammatory conditions. AIM The present study was aimed at embryo-fetal development toxicity evaluation of SFSE-G in Wistar rats as per guideline No. 414 of the Organization for Economic Co-operation and Development (OECD). MATERIAL AND METHODS Mated female rats w...
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ژورنال
عنوان ژورنال: Journal of Applied Pharmaceutical Science
سال: 2016
ISSN: 2231-3354
DOI: 10.7324/japs.2016.60927